Not to be defeated, Cleopatra orchestrated a plan to take back the throne and traveled to Syria with her younger half-sister Arsinoe IV. There, the two sisters gathered an invasion force and amassed troops along Egpyt's border in preparation to overthrow their brother. During such time, the Roman dictator Caesar arrived at the palace in Alexandria to collect debts owed to him and to reconcile the civil dispute between the two siblings. Cleopatra, realizing the opportunity to ally herself with Caesar, snuck inside the palace and seduced him. The alliance thus forced Arsinoe to join forces with her brother and attempt to remove Caesar and her sister. However, the combined military might of Caesar and Cleopatra proved far too strong, defeating the rival siblings in The Battle of The Nile. The victorious Cleopatra thus became queen of Egypt once again.
クレオパトラも負けずに王位奪還を企て、異母妹のアルシノエ4世とともにシリアに渡った。そこで姉弟は侵略軍を集め、エグピトの国境沿いに兵を集め、兄の打倒に備えた。そんな中、ローマの独裁者カエサルがアレクサンドリアの宮殿にやってきて、借金の取り立てと兄妹の内紛を和解させるためにやってきた。クレオパトラはカエサルと同盟を結ぶチャンスだと思い、宮殿に忍び込んでカエサルを誘惑した。こうして同盟を結んだアルシノエは兄と手を組み、カエサルと妹を排除しようとした。しかし、カエサルとクレオパトラの軍事力はあまりにも強大で、「ナイルの戦い」で対立する兄妹を打ち破った。勝利したクレオパトラは、再びエジプトの女王となった。